You should never play a strictly dominated strategy.
Rational play by rational players can lead to bad outcomes.
To figure out what actions you should choose in a game, a good first step is to figure out what are you payoffs ( what do you care about) and what other players' payoffs.
If you do not have a dominate strategy, put yourself in your opponents' shoes to try to predict what they will do. For example, in their shoes, you would not choose a dominated strategy.
Yale students are evil.